A new paper published on December 6th in the journal
Science once again tackles the question of whether elevated insulin drives the development of obesity (
1). Mice were generated that lack Jun kinases 1 and 2 specifically in immune cells, impairing their ability to produce inflammation while having very few off-target effects. These mice do not become insulin resistant when placed on a fattening diet, and their insulin levels do not increase one iota. Are they protected from obesity? People who read the last post should know the answer already.
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Published:
2012-12-13T18:19:00-08:00
Title:Is it Time to Re-write the Textbooks on Insulin and Obesity? Part II
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